2. Signaling Pathways
  3. PROTAC
  4. Ligands for E3 Ligase
  5. Ligands for E3 Ligase Inhibitor

Ligands for E3 Ligase Inhibitor

Ligands for E3 Ligase Isoform Comparison

Ligands for E3 Ligase Inhibitors (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-117937
    BC-1215 1507370-20-8 99.93%
    BC-1215 is a F-box protein 3 (Fbxo3) inhibitor. BC-1215 works by antagonizing of Fbxo3 on TRAF cytokine signaling and exhibits a low IC50 in vitro. BC-1215 can be used for the research of inflammation.
    BC-1215
  • HY-100947A
    cis VH-298 2097381-86-5
    cis VH-298 is a cis-form of VH-298 (HY-100947). VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM, used in PROTAC technology.
    cis VH-298
  • HY-120520
    Caylin-1 1207480-88-3
    Caylin-1 is an inhibitor of MDM2 and an analog of Nutlin-3. Caylin-1 can bind to Bcl-XL and is used in multi-target anticancer research.
    Caylin-1